Induction of endoplasmic reticulum-derived replication-competent membrane structures by West Nile virus non-structural protein 4B.

Replication of flaviviruses (family Flaviviridae) occurs in specialized virus-induced membrane structures (IMS). The cellular composition of these IMS varies for different flaviviruses implying different organelle origins for IMS biogenesis. The role of flavivirus non-structural (NS) proteins for th...

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Bibliographic Details
Main Authors: Pakieli H Kaufusi, James F Kelley, Richard Yanagihara, Vivek R Nerurkar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3896337?pdf=render