Major host factors involved in epithelial cell invasion of Campylobacter jejuni: Role of fibronectin, integrin beta1, FAK, Tiam-1 and DOCK180 in activating Rho GTPase Rac1

Major host factors involved in epithelial cell invasion of Campylobacter jejuni: Role of fibronectin, integrin beta1, FAK, Tiam-1 and DOCK180 in activating Rho GTPase Rac1

Host cell entry by the foodborne pathogen Campylobacter jejuni has been reported as one of the primary reasons of tissue damage in infected humans, however, molecular invasion mechanisms and cellular factors involved in this process are widely unclear. Here we used knockout cell lines derived from f...

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Bibliographic Details
Main Authors: Manja eBoehm, Malgorzata eKrause-Gruszczynska, Manfred eRohde, Nicole eTegtmeyer, Seiichiro eTakahashi, Omar A. Oyarzabal, Steffen eBackert
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Virulence
signalling
cellular invasion
molecular pathogenesis
Rho family GTPases
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2011.00017/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2011.00017/full

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