Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases

Abstract Inflammatory diseases have become increasingly prevalent with industrialization. To address this, numerous anti-inflammatory agents and molecular targets have been considered in clinical trials. Among molecular targets, protease-activated receptors (PARs) are abundantly recognized for their...

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Bibliographic Details
Main Authors: Dorothea M. Heuberger, Reto A. Schuepbach
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Thrombosis Journal
Online Access:http://link.springer.com/article/10.1186/s12959-019-0194-8