Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo

Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo

Respiratory Syncytial Virus (RSV) is an important human pathogen associated with substantial morbidity and mortality. The present study tested the hypothesis that RSV infection would increase matrix metalloproteinase (MMP)-9 expression, and that MMP-9 inhibition would decrease RSV replication both i...

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Bibliographic Details
Main Authors: Michele Y.F. Kong, Richard J. Whitley, Ning Peng, Robert Oster, Trenton R. Schoeb, Wayne Sullender, Namasivayam Ambalavanan, John Paul Clancy, Amit Gaggar, J. Edwin Blalock
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Viruses
Subjects:
respiratory syncytial virus
matrix metalloproteinase
cell
murine model
Online Access:http://www.mdpi.com/1999-4915/7/8/2817

Internet

http://www.mdpi.com/1999-4915/7/8/2817

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