Inference and effects of barcode multiplets in droplet-based single-cell assays

It is assumed that single-cell analyses capture one barcode per cell. Here, the authors show that up to 21% of cell barcodes on the 10X Chromium scATAC-seq assay may be derived from barcode multiplets.

Bibliographic Details
Main Authors: Caleb A. Lareau, Sai Ma, Fabiana M. Duarte, Jason D. Buenrostro
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14667-5