Pharmacokinetics of Azithromycin, Levofloxacin, and Ofloxacin in Rabbit Extraocular Tissues After Ophthalmic Administration

Pharmacokinetics of Azithromycin, Levofloxacin, and Ofloxacin in Rabbit Extraocular Tissues After Ophthalmic Administration

Abstract Introduction Azithromycin demonstrates high tissue distribution and prolonged elimination half-life. In this study, we monitored the pharmacokinetics of a single ophthalmic administration of 1% azithromycin ophthalmic solution containing polycarbophil in the extraocular tissues, including t...

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Bibliographic Details
Main Authors: Tatsuya Sakai, Keisuke Shinno, Masaaki Kurata, Akio Kawamura
Format: Article
Language:English
Published: Adis, Springer Healthcare 2019-08-01
Series:Ophthalmology and Therapy
Subjects:
Azithromycin
Conjunctiva
Cornea
Drug concentration profile
Eyelid
Levofloxacin
Online Access:http://link.springer.com/article/10.1007/s40123-019-00205-0

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http://link.springer.com/article/10.1007/s40123-019-00205-0

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