Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway.

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway.

Lung squamous cell carcinoma (SqCC), the second most common subtype of lung cancer, is strongly associated with tobacco smoking and exhibits genomic instability. The cellular origins and molecular processes that contribute to SqCC formation are largely unexplored. Here we show that human basal stem...

Full description

Bibliographic Details
Main Authors: Clare E Weeden, Yunshun Chen, Stephen B Ma, Yifang Hu, Georg Ramm, Kate D Sutherland, Gordon K Smyth, Marie-Liesse Asselin-Labat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2000731

Internet

https://doi.org/10.1371/journal.pbio.2000731

Similar Items