Optimizing Surveillance Performance of Alpha-Fetoprotein by Selection of Proper Target Population in Chronic Hepatitis B.

Although alpha-fetoprotein (AFP) is the most widely used biomarker in hepatocellular carcinoma (HCC) surveillance, disease activity may also increase AFP levels in chronic hepatitis B (CHB). Since nucleos(t)ide analog (NA) therapy may reduce not only HBV viral loads and transaminase levels but also...

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Main Authors: Jung Wha Chung, Beom Hee Kim, Chung Seop Lee, Gi Hyun Kim, Hyung Rae Sohn, Bo Young Min, Joon Chang Song, Hyun Kyung Park, Eun Sun Jang, Hyuk Yoon, Jaihwan Kim, Cheol Min Shin, Young Soo Park, Jin-Hyeok Hwang, Sook-Hyang Jeong, Nayoung Kim, Dong Ho Lee, Jaebong Lee, Soyeon Ahn, Jin-Wook Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5172583?pdf=render