Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy

The type II AAA+ protein p97 is involved in numerous cellular activities, including endoplasmic reticulum-associated degradation, transcription activation, membrane fusion and cell-cycle control. These activities are at least in part regulated by the ubiquitin system, in which p97 is thought to targ...

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Bibliographic Details
Main Authors: Heidi O. Yeung, Andreas Förster, Cecilia Bebeacua, Hajime Niwa, Caroline Ewens, Ciarán McKeown, Xiaodong Zhang, Paul S. Freemont
Format: Article
Language:English
Published: The Royal Society 2014-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130142