Oxygen dependence of nitric oxide-mediated signaling

Nitric oxide (·NO) is a biologically important short-lived free radical signaling molecule. Both the enzymatic synthesis and the predominant forms of cellular metabolism of ·NO are oxygen-dependent. For these reasons, changes in local oxygen concentrations can have a profound influence on steady-st...

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Bibliographic Details
Main Authors: Jason R. Hickok, Divya Vasudevan, Kate Jablonski, Douglas D. Thomas
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
sGC
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231712000031