Purine Nucleotides in the Regulation of Brown Adipose Tissue Activity

Non-shivering thermogenesis in mammalian brown adipose tissue is a powerful mechanism to defend normothermia in cold climates. To minimize the loss of chemical energy, the central functional component, mitochondrial uncoupling protein 1, UCP1, must be tightly regulated. The canonical pathway of UCP1...

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Bibliographic Details
Main Authors: Andrea Bast-Habersbrunner, Tobias Fromme
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00118/full