Efficient enrichment of hepatic cancer stem-like cells from a primary rat HCC model via a density gradient centrifugation-centered method.

BACKGROUND: Because few definitive markers are available for hepatic cancer stem cells (HCSCs), based on physical rather than immunochemical properties, we applied a novel method to enrich HCSCs. METHODOLOGY: After hepatic tumor cells (HTCs) were first isolated from diethylinitrosamine-induced F344...

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Bibliographic Details
Main Authors: Wei-hui Liu, Xing Wang, Nan You, Kai-shan Tao, Tao Wang, Li-jun Tang, Ke-feng Dou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338461?pdf=render