Identification of Differentially Methylated Regions Associated with a Knockout of SUV39H1 in Prostate Cancer Cells

Epigenetic alterations, such as histone methylations, affect the pathogenesis of tumors including prostate cancer (PCa). Previously, we reported that metformin reduced SUV39H1, a histone methyltransferase of H3 Lys9, to inhibit the migration of PCa cells. Since histone methylation is functionally li...

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Bibliographic Details
Main Authors: Wenbo Yan, Yuqi Guo, Fangxi Xu, Deepak Saxena, Xin Li
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/10/1188