Dopamine Neurons Mediate Learning and Forgetting through Bidirectional Modulation of a Memory Trace

Summary: It remains unclear how memory engrams are altered by experience, such as new learning, to cause forgetting. Here, we report that short-term aversive memory in Drosophila is encoded by and retrieved from the mushroom body output neuron MBOn-γ2α′1. Pairing an odor with aversive electric shock...

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Bibliographic Details
Main Authors: Jacob A. Berry, Anna Phan, Ronald L. Davis
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718314967