CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia

CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia

Throughout metazoans, germ cells undergo incomplete cytokinesis to form syncytia connected by intercellular bridges. Gamete formation ultimately requires bridge closure, yet how bridges are reactivated to close is not known. The most conserved bridge component is centralspindlin, a complex of the Rh...

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Bibliographic Details
Main Authors: Kian-Yong Lee, Rebecca A Green, Edgar Gutierrez, J Sebastian Gomez-Cavazos, Irina Kolotuev, Shaohe Wang, Arshad Desai, Alex Groisman, Karen Oegema
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
germline syncytia
intercellular bridge
centralspindlin
MgcRacGAP
Kinesin-6
ring canal
Online Access:https://elifesciences.org/articles/36919

Internet

https://elifesciences.org/articles/36919

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