PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo

PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo

Abstract Objective To study whether minimal doses of arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and lipoxin A4 (LXA4) and brain-derived neurotrophic factor (BDNF), when used in combination can protect RIN5F cells from chemical-induced cytotoxicity. As a corolla...

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Bibliographic Details
Main Authors: Siresha Bathina, Undurti N. Das
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Lipids in Health and Disease
Subjects:
Brain derived neurotrophic factor
Polyunsaturated fatty acid
Lipoxin A4
RIN5F cells
Inflammation
Antioxidants
Online Access:https://doi.org/10.1186/s12944-019-1164-7

Internet

https://doi.org/10.1186/s12944-019-1164-7

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