Comparison of the efficacy of a commercial inactivated influenza A/H1N1/pdm09 virus (pH1N1) vaccine and two experimental M2e-based vaccines against pH1N1 challenge in the growing pig model.

Comparison of the efficacy of a commercial inactivated influenza A/H1N1/pdm09 virus (pH1N1) vaccine and two experimental M2e-based vaccines against pH1N1 challenge in the growing pig model.

Swine influenza A viruses (IAV-S) found in North American pigs are diverse and the lack of cross-protection among heterologous strains is a concern. The objective of this study was to compare a commercial inactivated A/H1N1/pdm09 (pH1N1) vaccine and two novel subunit vaccines, using IAV M2 ectodomai...

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Bibliographic Details
Main Authors: Tanja Opriessnig, Phillip C Gauger, Priscilla F Gerber, Alessandra M M G Castro, Huigang Shen, Lita Murphy, Paul Digard, Patrick G Halbur, Ming Xia, Xi Jiang, Ming Tan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5790244?pdf=render

Internet

http://europepmc.org/articles/PMC5790244?pdf=render

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