Effect of Food and an Animal’s Sex on P-Glycoprotein Expression and Luminal Fluids in the Gastrointestinal Tract of Wistar Rats

The rat is one of the most commonly used animal models in pre-clinical studies. Limited information between the sexes and the effect of food consumption on the gastrointestinal (GI) physiology, however, is acknowledged or understood. This study aimed to investigate the potential sex differences and...

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Bibliographic Details
Main Authors: Liu Dou, Francesca K. H. Gavins, Yang Mai, Christine M. Madla, Farhan Taherali, Mine Orlu, Sudaxshina Murdan, Abdul W. Basit
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/4/296