Enhancing the aqueous solubility and dissolution of olanzapine using freeze-drying

Enhancing the aqueous solubility and dissolution of olanzapine using freeze-drying

The aim of the present study was to develop an olanzapine freeze-dried tablet (FDT). The solubility and dissolution rate of poorly water-soluble olanzapine was improved by preparing a freeze-dried tablet of olanzapine using the freeze-drying technique . The FDT was prepared by dispersing the drug in...

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Bibliographic Details
Main Authors:	Mudit Dixit, Ashwini Gopalkrishna Kini, Parthasarthi Keshavarao Kulkarni
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2011-12-01
Series:	Brazilian Journal of Pharmaceutical Sciences
Subjects:	Comprimidos liofilizados Olanzapina Liofilização Freeze-dried tablets Olanzapine Freeze-drying
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400011

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