Enhancing the aqueous solubility and dissolution of olanzapine using freeze-drying

The aim of the present study was to develop an olanzapine freeze-dried tablet (FDT). The solubility and dissolution rate of poorly water-soluble olanzapine was improved by preparing a freeze-dried tablet of olanzapine using the freeze-drying technique . The FDT was prepared by dispersing the drug in...

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Bibliographic Details
Main Authors: Mudit Dixit, Ashwini Gopalkrishna Kini, Parthasarthi Keshavarao Kulkarni
Format: Article
Language:English
Published: Universidade de São Paulo 2011-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400011