Enhancing the aqueous solubility and dissolution of olanzapine using freeze-drying
The aim of the present study was to develop an olanzapine freeze-dried tablet (FDT). The solubility and dissolution rate of poorly water-soluble olanzapine was improved by preparing a freeze-dried tablet of olanzapine using the freeze-drying technique . The FDT was prepared by dispersing the drug in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2011-12-01
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Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400011 |