Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems

Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems

Abstract Background Recombinant Modified Vaccinia Virus Ankara has been employed as a safe and potent viral vector vaccine against infectious diseases and cancer. We generated recMVAs encoding norovirus GII.4 genotype capsid protein by using a marker-based approach and a BAC-based system. In the mar...

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Bibliographic Details
Main Authors: Franziska Kugler, Ingo Drexler, Ulrike Protzer, Dieter Hoffmann, Hassan Moeini
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Virology Journal
Subjects:
Bacterial artificial chromosome
Recombinant MVA
Self-excising
Norovirus
Online Access:http://link.springer.com/article/10.1186/s12985-019-1212-y

Internet

http://link.springer.com/article/10.1186/s12985-019-1212-y

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