CHK Methylation Is Elevated in Colon Cancer Cells and Contributes to the Oncogenic Properties

Src is an important oncogene that plays key roles in multiple signal transduction pathways. Csk-homologous kinase (CHK) is a kinase whose molecular roles are largely uncharacterized. We previously reported expression of CHK in normal human colon cells, and decreased levels of CHK protein in colon ca...

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Bibliographic Details
Main Authors: Shudong Zhu, Yan Zhu, Qiuwen Wang, Yi Zhang, Xialing Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CHK
FHC
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.708038/full