Ribosomal DNA deletions modulate genome-wide gene expression: "rDNA-sensitive" genes and natural variation.

The ribosomal rDNA gene array is an epigenetically-regulated repeated gene locus. While rDNA copy number varies widely between and within species, the functional consequences of subtle copy number polymorphisms have been largely unknown. Deletions in the Drosophila Y-linked rDNA modifies heterochrom...

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Bibliographic Details
Main Authors: Silvana Paredes, Alan T Branco, Daniel L Hartl, Keith A Maggert, Bernardo Lemos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3080856?pdf=render