Perspective: The Challenge of Clinical Decision-Making for Drug Treatment in Older People. The Role of Multidimensional Assessment and Prognosis
A complex decision path with a careful evaluation of the risk-benefit ratio is mandatory for drug treatment in advanced age. Enrolment biases in randomized clinical trials (RCTs) cause an underrepresentation of older individuals. In high-risk frail older subjects, the lack of RCTs makes clinical dec...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-01-01
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Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmed.2014.00061/full |