Perspective: The Challenge of Clinical Decision-Making for Drug Treatment in Older People. The Role of Multidimensional Assessment and Prognosis

A complex decision path with a careful evaluation of the risk-benefit ratio is mandatory for drug treatment in advanced age. Enrolment biases in randomized clinical trials (RCTs) cause an underrepresentation of older individuals. In high-risk frail older subjects, the lack of RCTs makes clinical dec...

Full description

Bibliographic Details
Main Authors: Alberto ePilotto, Daniele eSancarlo, Julia eDaragjati, Francesco ePanza
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2014.00061/full