Comet Assay: A Method to Evaluate Genotoxicity of Nano-Drug Delivery System
Introduction: Drug delivery systems could induce cellular toxicity as side effect of nanomaterials. The mechanism of toxicity usually involves DNA damage. The comet assay or single cell gel electrophoresis (SCGE) is a sensitive method for detecting strand damages in the DNA of a cell with applicatio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2011-08-01
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Series: | BioImpacts |
Subjects: | |
Online Access: | http://dx.doi.org/10.5681/bi.2011.012 |