A radiosensitizer, gallotannin-rich extract from Bouea macrophylla seeds, inhibits radiation-induced epithelial-mesenchymal transition in breast cancer cells

A radiosensitizer, gallotannin-rich extract from Bouea macrophylla seeds, inhibits radiation-induced epithelial-mesenchymal transition in breast cancer cells

Abstract Background Radioresistance can pose a significant obstacle to the effective treatment of breast cancers. Epithelial–mesenchymal transition (EMT) is a critical step in the acquisition of stem cell traits and radioresistance. Here, we investigated whether Maprang seed extract (MPSE), a gallot...

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Bibliographic Details
Main Authors: Jiraporn Kantapan, Siwaphon Paksee, Aphidet Duangya, Padchanee Sangthong, Sittiruk Roytrakul, Sucheewin Krobthong, Wipob Suttana, Nathupakorn Dechsupa
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Radiosensitizer
EMT
Cancer stem cells
Breast cancer
Senescence
Apoptosis
Online Access:https://doi.org/10.1186/s12906-021-03363-6

Internet

https://doi.org/10.1186/s12906-021-03363-6

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