Effect of cytochrome P450 2C19*17 allelic variant on cardiovascular and cerebrovascular outcomes in clopidogrel-treated patients: A systematic review and meta-analysis

Effect of cytochrome P450 2C19*17 allelic variant on cardiovascular and cerebrovascular outcomes in clopidogrel-treated patients: A systematic review and meta-analysis

Background: We aimed to evaluate the associations of gain-of-function allele of CYP2C19* 17 and risk of clinical events in clopidogrel-treated patients with cardiovascular and cerebrovascular diseases (CCVDs). Materials and Methods: Literature search was conducted in PubMed, EMBASE, and Cochrane Lib...

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Bibliographic Details
Main Authors: Bo Huang, De-Jun Cui, Ying Ren, Bin Han, Da-Ping Yang, Xun Zhao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Bleeding
cardiovascular and cerebrovascular disease
clopidogrel
CYP2C19* 17
high platelet reactivity
major adverse cardiovascular and cerebrovascular events
meta-analysis
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=109;epage=109;aulast=Huang

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http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=109;epage=109;aulast=Huang

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