Computational analysis reveals histotype-dependent molecular profile and actionable mutation effects across cancers

Abstract Background Comprehensive mutational profiling data now available on all major cancers have led to proposals of novel molecular tumor classifications that modify or replace the established organ- and tissue-based tumor typing. The rationale behind such molecular reclassifications is that gen...

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Bibliographic Details
Main Authors: Daniel Heim, Grégoire Montavon, Peter Hufnagl, Klaus-Robert Müller, Frederick Klauschen
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Genome Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13073-018-0591-9