Dysregulation of M segment gene expression contributes to influenza A virus host restriction.

Dysregulation of M segment gene expression contributes to influenza A virus host restriction.

The M segment of the 2009 pandemic influenza A virus (IAV) has been implicated in its emergence into human populations. To elucidate the genetic contributions of the M segment to host adaptation, and the underlying mechanisms, we examined a panel of isogenic viruses that carry avian- or human-derive...

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Bibliographic Details
Main Authors: Brenda M Calderon, Shamika Danzy, Gabrielle K Delima, Nathan T Jacobs, Ketaki Ganti, Megan R Hockman, Graeme L Conn, Anice C Lowen, John Steel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007892

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https://doi.org/10.1371/journal.ppat.1007892

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