The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia

Abstract Glucocorticoids, such as dexamethasone and prednisolone, are widely used in cancer treatment. Different hematological malignancies respond differently to this treatment which, as could be expected, correlates with treatment outcome. In this study, we have used a glucocorticoid-induced gene...

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Bibliographic Details
Main Authors: Kinjal Shah, Mehreen Ahmed, Julhash U. Kazi
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00148-5