The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

The obligate intracellular parasite Toxoplasma gondii secretes effector proteins into the host cell that manipulate the immune response allowing it to establish a chronic infection. Crosses between the types I, II and III strains, which are prevalent in North America and Europe, have identified seve...

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Bibliographic Details
Main Authors: Wendy Niedelman, Daniel A Gold, Emily E Rosowski, Joris K Sprokholt, Daniel Lim, Ailan Farid Arenas, Mariane B Melo, Eric Spooner, Michael B Yaffe, Jeroen P J Saeij
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3386190?pdf=render

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http://europepmc.org/articles/PMC3386190?pdf=render

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