Novel variants in the ACTA2 and MYH11 genes in a Cypriot family with thoracic aortic aneurysms: a case report

Novel variants in the ACTA2 and MYH11 genes in a Cypriot family with thoracic aortic aneurysms: a case report

Abstract Background Thoracic aortic aneurysm (TAA) and/or thoracic aortic aneurysm and dissection (TAAD) is characterized by a considerable risk of morbidity and mortality of affected individuals. It is inherited in an autosomal dominant pattern and the 20% of patients with non-syndromic TAA have a...

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Bibliographic Details
Main Authors: Anna Keravnou, Evy Bashiardes, Kyriaki Michailidou, Marinos Soteriou, Areti Moushi, Marios Cariolou
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Medical Genetics
Subjects:
Aortic aneurysm
ACTA2
MYH11
Cyprus
Targeted next generation sequencing
Online Access:http://link.springer.com/article/10.1186/s12881-018-0728-0

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http://link.springer.com/article/10.1186/s12881-018-0728-0

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