Dynamic chromatin organization during foregut development mediated by the organ selector gene PHA-4/FoxA.
Central regulators of cell fate, or selector genes, establish the identity of cells by direct regulation of large cohorts of genes. In Caenorhabditis elegans, foregut (or pharynx) identity relies on the FoxA transcription factor PHA-4, which activates different sets of target genes at various times...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-08-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2920861?pdf=render |