Oxidant/Antioxidant Profile in the Thoracic Aneurysm of Patients with the Loeys-Dietz Syndrome

Patients with the Loeys-Dietz syndrome (LDS) have mutations in the TGF-βR1, TGF-βR2, and SMAD3 genes. However, little is known about the redox homeostasis in the thoracic aortic aneurysms (TAA) they develop. Here, we evaluate the oxidant/antioxidant profile in the TAA tissue from LDS patients and co...

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Main Authors: Maria Elena Soto, Lináloe G. Manzano-Pech, Verónica Guarner-Lans, Jorge A. Díaz-Galindo, Xicoténcatl Vásquez, Vicente Castrejón-Tellez, Ricardo Gamboa, Claudia Huesca, Giovanny Fuentevilla-Alvárez, Israel Pérez-Torres
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/5392454