Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors

Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors

Leishmaniasis is considered as one of the major neglected tropical diseases due to its magnitude and wide geographic distribution. Leishmania braziliensis, responsible for cutaneous leishmaniasis, is the most prevalent species in Brazil. Superoxide dismutase (SOD) belongs to the antioxidant pathway...

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Bibliographic Details
Main Authors: Camila C. Bitencourt Brito, Hélder Vinicius Carneiro da Silva, Daci José Brondani, Antonio Rodolfo de Faria, Rafael Matos Ximenes, Ivanildo Mangueira da Silva, Julianna F. C. de Albuquerque, Marcelo Santos Castilho
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
leishmania
superoxide dismutase
thiazole derivatives
thermal shift assay
Online Access:http://dx.doi.org/10.1080/14756366.2018.1550752

Internet

http://dx.doi.org/10.1080/14756366.2018.1550752

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