Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells.

Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells.

Reprogramming acinar cells into insulin producing cells using adenoviral (Ad)-mediated delivery of Pdx1, Ngn3 and MafA (PNM) is an innovative approach for the treatment of diabetes. Here, we aimed to investigate the molecular mechanisms involved in this process and in particular, the role of microRN...

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Bibliographic Details
Main Authors: Joan Teichenne, Meritxell Morró, Alba Casellas, Veronica Jimenez, Noelia Tellez, Adrien Leger, Fatima Bosch, Eduard Ayuso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4686894?pdf=render

Internet

http://europepmc.org/articles/PMC4686894?pdf=render

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