In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization

In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization

CD4 T cells are key mediators of adaptive immune responses during infection and vaccination. Within secondary lymphoid organs, helper CD4 T cells, particularly those residing in germinal centers known as follicular helper T cells (Tfh), provide critical help to B-cells to promote their survival, iso...

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Bibliographic Details
Main Authors: Eirini Moysi, Perla M. Del Rio Estrada, Fernanda Torres-Ruiz, Gustavo Reyes-Terán, Richard A. Koup, Constantinos Petrovas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
lymph nodes
Tfh
confocal imaging
tissue architecture
HIV reservoir
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.683396/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.683396/full

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