Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery

Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery

Hydroxyzine HCL (HHCL) is an antihistamine, used for the treatment of allergic skin conditions. The purpose of this study was to achieve a dual phase drug delivery rate across the intact skin, to enhance HHCL permeation through the stratum corneum, to assess the peripheral H1-antihistaminic activity...

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Bibliographic Details
Main Authors: Dalia Farag A. El-Telbany, Rania Farag A. El-Telbany, Sherin Zakaria, Kawkab A. Ahmed, Yasmin A. El-Feky
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Hydroxyzine HCL (HHCL)
Solid lipid nanoparticles (SLNs)
W/O/W type double emulsification method
Transdermal gel
Atopic dermatitis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221009148

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http://www.sciencedirect.com/science/article/pii/S0753332221009148

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