Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults.

The role of mitochondrial dysfunction and oxidative stress has been extensively characterized in the aetiology of sarcopenia (aging-associated loss of muscle mass) and muscle wasting as a result of muscle disuse. What remains less clear is whether the decline in skeletal muscle mitochondrial oxidati...

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Bibliographic Details
Main Authors: Adeel Safdar, Mazen J Hamadeh, Jan J Kaczor, Sandeep Raha, Justin Debeer, Mark A Tarnopolsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2875392?pdf=render