Solid solutions vs. solid dispersions: the impact of formulation parameters
Matrix films were prepared with drugs with different aqueous solubility (metoprolol tartrate, ibuprofen and diclofenac Na) and different polymers (ethylcellulose, Eudragit RS and Eudragit RL). Solid solutions (drug dissolved) and solid dispersions (drug dispersed) were obtained. The drug release was...
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| Format: | Article |
| Language: | English |
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ALIES - Associação Lusófona para o Desenvolvimento da Investigação e do Ensino das Ciências da Saúde
2013-12-01
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| Series: | Journal Biomedical and Biopharmaceutical Research (BBR) |
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| Online Access: | http://www.alies.pt/BBR%20Editions/Vol-10-2-2013/Article9_10n2.pdf |