A new selective, and sensitive method for the determination of lixivaptan, a vasopressin 2 (V2)-receptor antagonist, in mouse plasma and its application in a pharmacokinetic study
A new, selective and sensitive HPLC method for the determination of lixivaptan, an oral selective vasopressin 2 (V2)-receptor antagonist, was investigated and validated. A Waters symmetry C18 column was used as a stationary phase in isocratic elution mode using a mobile phase composed of KH2PO4 (100...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2018-07-01
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Series: | Open Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.1515/chem-2018-0063 |