DNA Damage Response in the Adaptive Arm of the Immune System: Implications for Autoimmunity

DNA Damage Response in the Adaptive Arm of the Immune System: Implications for Autoimmunity

In complex environments, cells have developed molecular responses to confront threats against the genome and achieve the maintenance of genomic stability assuring the transfer of undamaged DNA to their progeny. DNA damage response (DDR) mechanisms may be activated upon genotoxic or environmental age...

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Bibliographic Details
Main Authors: Theodora Manolakou, Panayotis Verginis, Dimitrios T. Boumpas
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
DNA damage response
DNA repair
autoimmunity
adaptive immunity
lymphocytes
B cells
Online Access:https://www.mdpi.com/1422-0067/22/11/5842

Internet

https://www.mdpi.com/1422-0067/22/11/5842

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