Structural Modifications of 3-triazeneindoles and Their Increased Activity Against <i>Mycobacterium tuberculosis</i>

Structural Modifications of 3-triazeneindoles and Their Increased Activity Against <i>Mycobacterium tuberculosis</i>

We synthesized 100 novel indole-based compounds with polyaza-functionalities, including 3-triazeneindoles, and tested their activity in vitro against laboratory <i>M. tuberculosis </i>H37Rv and clinical izoniazid-resistant CN-40 isolates, using gross and fine titration approaches. Here w...

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Bibliographic Details
Main Authors: Konstantin B. Majorov, Boris V. Nikonenko, Pavel Yu. Ivanov, Lyudmila N. Telegina, Alexander S. Apt, Valeria S. Velezheva
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Antibiotics
Subjects:
tuberculosis
drug candidates
3-triazenoindoles.
Online Access:https://www.mdpi.com/2079-6382/9/6/356

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https://www.mdpi.com/2079-6382/9/6/356

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