Reduced Efficacy of Mesenchymal Stromal Cells in Preventing Graft-Versus-Host Disease in an in Vivo Model of Haploidentical Bone Marrow Transplant with Leukemia

Reduced Efficacy of Mesenchymal Stromal Cells in Preventing Graft-Versus-Host Disease in an in Vivo Model of Haploidentical Bone Marrow Transplant with Leukemia

Mesenchymal stromal cell (MSC) immunosuppressive properties have been applied to treat graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplants (HSCTs). We have previously demonstrated that MSC infusions early after haplo-HSCT prevent GVHD in a haploidentical-HSCT mouse mod...

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Bibliographic Details
Main Authors: Alberto Oviedo, Rosa Yañez, Isabel Colmenero, Montserrat Aldea, Antonio Rubio, Juan Antonio Bueren, María Luisa Lamana
Format: Article
Language:English
Published: SAGE Publishing 2013-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X657666

Internet

https://doi.org/10.3727/096368912X657666

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