Designing Clinical Trials in Pediatric Nonalcoholic Steatohepatitis: Tips for Patient Selection and Appropriate Endpoints

Nonalcoholic fatty liver disease (NAFLD) is common in children and may progress to nonalcoholic steatohepatitis (NASH), advanced fibrosis, and even cirrhosis in childhood or early adulthood, indicating the need for pharmacologic treatment in this age group. Multiple trials are evaluating different t...

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Bibliographic Details
Main Authors: Naim Alkhouri, Rohit Kohli, Ariel E. Feldstein
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1449