Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo.

Temporins are antimicrobial peptides secreted by the granular glands of the European red frog (Rana temporaria). They are 10-14 amino acid long polypeptides active prevalently against gram positive bacteria. This study shows that a synthetic temporin B analogue (TB-YK), acquires the capacity to act...

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Bibliographic Details
Main Authors: Rosanna Capparelli, Alessandra Romanelli, Marco Iannaccone, Nunzia Nocerino, Raffaella Ripa, Soccorsa Pensato, Carlo Pedone, Domenico Iannelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2747021?pdf=render