Long-term evolution of the epithelial cell secretome in preclinical 3D models of the human bronchial epithelium

Abstract The human bronchial epithelium is the first line of defense against atmospheric particles, pollutants, and respiratory pathogens such as the novel SARS-CoV-2. The epithelial cells form a tight barrier and secrete proteins that are major components of the mucosal immune response. Functional...

Full description

Bibliographic Details
Main Authors: Daniel Sanchez-Guzman, Sonja Boland, Oliver Brookes, Claire Mc Cord, René Lai Kuen, Valentina Sirri, Armelle Baeza Squiban, Stéphanie Devineau
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86037-0