Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant

Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant

The advent of large-scale in vitro differentiation of human stem cell-derived insulin-producing cells (SCIPC) has brought us closer to treating diabetes using stem cell technology. However, decades of experiences from islet transplantation show that ischemia-induced islet cell death after transplant...

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Bibliographic Details
Main Authors: Gaetano Faleo, Holger A. Russ, Steven Wisel, Audrey V. Parent, Vinh Nguyen, Gopika G. Nair, Jonathan E. Freise, Karina E. Villanueva, Gregory L. Szot, Matthias Hebrok, Qizhi Tang
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Stem Cell Reports
Subjects:
stem cell-derived insulin-producing cells
type 1 diabetes
islet transplant
ischemia
hypoxia
nutrient deprivation
graft survival
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117303223

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http://www.sciencedirect.com/science/article/pii/S2213671117303223

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