Artesunate abolishes germinal center B cells and inhibits autoimmune arthritis.

The antimalarial drug artemisinin and its derivatives exhibit potent immunosuppressive activity in several autoimmune disease models, however the mechanisms are not well-understood. This study was designed to investigate the therapeutic effects and the underlying mechanisms of the artemisinin analog...

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Bibliographic Details
Main Authors: Lifei Hou, Katharine E Block, Haochu Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4130578?pdf=render