Rheostats and toggle switches for modulating protein function.

The millions of protein sequences generated by genomics are expected to transform protein engineering and personalized medicine. To achieve these goals, tools for predicting outcomes of amino acid changes must be improved. Currently, advances are hampered by insufficient experimental data about nonc...

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Bibliographic Details
Main Authors: Sarah Meinhardt, Michael W Manley, Daniel J Parente, Liskin Swint-Kruse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3875437?pdf=render